|
KMID : 0380620120440010089
|
|
Korean Journal of Food Science and Technology
2012 Volume.44 No. 1 p.89 ~ p.93
|
|
|
The Antioxidant and Skin Whitening Effect of Artemisia iwayomogi Extracts
|
|
Seo Eun-Jong
Hong Eun-Suk
Choi Min-Hee
Kim Ki-Sun
Lee Sung-Jun
|
|
|
Abstract
|
|
|
|
The purpose of this study was to investigate the antioxidant and skin whitening effects of Artemisia iwayomogi extract. Artemisia iwayomogi was extracted with 100% ethanol and water. The antioxidative and skin whitening effects of these extracts were determined with in vitro assays by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method assessing the inhibitory effects on tyrosinase activity and melanogenesis in B16 melanoma cells. Radical scavenging activity of the extracts was tested by DPPH assay which showed a high DPPH radical scavenging activity (SC50; 17.1 ppm in EtOH, 198.4 ppm in water). In term of tyrosinase inhibitory activity, Artemisia iwayomogi ethanol extract showed high inhibition activity (IC50: 481.8 ppm). In B16 mouse melanoma cells, the ethanol extract significantly inhibited melanin synthesis by 36.8% at a concentration of 50 ppm. These results suggest that Artemisia iwayomogi ethanol extract has significant antioxidant activity and whitening activity.
|
|
|
KEYWORD
|
|
|
Artemisia iwayomogi, antioxidant, whitening, tyrosinase
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|